Good for Basic Compounds | Alternate for USP® L10 | Use in RP or NP
Useful for basic compounds in Reversed Phase (RP), HPLC when
different selectivity from C8 and C18 columns is desired. Also used for Normal
Phase (NP), HPLC as they are less retentive than un-modified silica phases and
offer different selectivity from Amino and Diol columns. Due to faster
equilibrium compared with other NP phases, they are often the choice for
gradient NP methods.
A common use for Cyano columns is to remove polar compounds from complex mixtures
that also contain non-polar compounds.