Another feature of C8 columns is that they may be able to retain some slightly polar compounds that C18 cannot retain very well.
TYPE-C™ Silica is the unique "silica-hydride" that has a double point of attachment of the C8 ligand with direct silicon-carbon bonds, no end capping is needed. This makes the Cogent Bidentate C8™ phase the most stable C8 on the market. The typical
water shell that is found in other stationary phases allows for some very unique
features including operation in ANP (Aqueous Normal Phase), NP (Normal Phase) or
RP
(Reversed Phase), and modes can be changed without hysteresis. This C18 column
is
very hydrophobic compared to most C18 columns and has its own page. Please click HERE for ordering information..
Our spherical, low metal content silica with exhaustive end-capping is the most commonly used column for Reversed Phase methods. These include the MOST POPULAR Cogent RP C8™ - Cogent HPS C8™ and other C8 columns including Similars™ C8 .
Irregular silica bonded C8 with and without end-capping for older USP® monographs or in-house methods matches with the stationary phases used to develop the monographs. The Cogent MicroBee C8™ is made to be similar to µBondapak® C8.