These Cogent, TYPE-C™, Amide Hydride™, HPLC columns have an ethyl amide, functional group, bonded to the silica hydride particle with direct, silicon-carbon bonds. This makes the stationary phase extremely stable, even in low pH conditions and it doesn't make permanent associations with acetone like amino phases. Amide functional groups are never ionic under any chromatographic conditions providing some advantages.
The Cogent Amide™ phase is recommended for Aqueous Normal Phase (ANP mode) or Normal-Phase (NP mode) separations of biomolecules, macro-molecules, carbohydrates, peptides, polysaccharides and tryptic digests.
Click HERE for a listing of all Cogent TYPE-C™ Stationary Phases.